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This results in a buildup of fluid in the lungs, causing shortness of breath and fatigue.

A complex clinical syndrome, heart failure leads to increased retention of salt and water by the kidneys. It is often triggered by damage to the heart from, for example, a heart attack or a viral infection. Heart failure is one of the leading causes of hospitalization in the United States, with about two heart failure hospitalizations occurring every minute. The study also provides evidence that the treatment with valsartan may be slightly safer for patients with advanced heart failure. Louis suggests that a widely used heart failure drug named sacubitril/valsartan is no better than valsartan alone in patients with severe heart failure. A new study led by researchers at Washington University School of Medicine in St.